Taikang Chemical
宁波台康化工有限公司 Ningbo Taikang Chemical Co., Ltd.
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Pharma & Agro Intermediate

p-Toluenesulfonylmethyl Isocyanide
Tosylmethyl Isocyanide (TosMIC)

A workhorse C1 synthon for heterocycle construction — the industrial route to Bempedoic acid and the fungicide Fludioxonil. Multi-hundred-kg supply with accelerated-stability-backed 6-month shelf life.

CAS 36635-61-7 C₉H₉NO₂S MW 195.24 DG: UN 2811 · Class 6.1 · PG III Purity ≥ 99.0% (HPLC)
p-Toluenesulfonylmethyl Isocyanide Commercial TosMIC — off-white crystalline powder

Where TosMIC Fits in Your Synthesis

A one-carbon unit for imidazole, oxazole, thiazole and pyrrole rings — each downstream target branches independently from TosMIC.

This Product
TosMIC
p-Toluenesulfonylmethyl isocyanide
CAS 36635-61-7
WE SUPPLY
Downstream · Pharma
Bempedoic Acid
cholesterol-lowering API (imidazole C1 core)
Downstream · Agro
Fludioxonil
phenylpyrrole fungicide (pyrrole ring)
Downstream · Synthesis
Imidazoles · Oxazoles · Thiazoles
van Leusen heterocycle toolbox · aldehyde → nitrile

Product Specifications

Specifications per manufacturer standard Q/FH 011-2019; accelerated stability verified over 3 commercial batches (25 °C / 60% RH, 6 months).

Test ParameterSpecification
AppearanceAlmost-white to light-yellow crystalline powder
Melting Point109–113 °C
Purity (HPLC)≥ 99.0%
TosMIC precursor residue (TOSMF, HPLC)≤ 0.3%
Loss on Drying / Water≤ 0.5%
Molecular Formula / MWC₉H₉NO₂S / 195.24

Three Outlets from One C1 Synthon

Two flagship downstream molecules plus broad heterocycle chemistry — all anchored to our industrial-grade supply.

Bempedoic Acid (ETC-1002)

Cholesterol-lowering API (ATP citrate lyase inhibitor). TosMIC builds the imidazole/pyrrole C1 core in the key ring-forming step. Stable, multi-hundred-kg lots support commercial campaigns.

Source: product application sheet

Fludioxonil

Non-systemic broad-spectrum phenylpyrrole fungicide (seed treatment / foliar). TosMIC is the C1 synthon for the pyrrole ring construction in industrial synthesis.

Source: product application sheet

General Heterocycle Chemistry

van Leusen imidazole / oxazole / thiazole / pyrrole syntheses; convert aldehydes to nitriles; midazole ligands for Pd-catalyzed mono- and bi-arylation.

Source: TDS usage notes

Packing & Logistics

Export-ready packing, full documentation and DG handling where applicable.

Packing Packing
  • Standard Packing: 25 kg / 20 kg fiber drum with aluminum-foil liner (custom on request)
  • Documentation: COA, TDS, SDS per batch
  • Dangerous Goods: UN 2811, Class 6.1 (TOXIC SOLID, ORGANIC, N.O.S.), PG III — DG-experienced export desk
  • Storage: Ventilated, dry warehouse; protect from moisture, heat and sunlight; keep away from food / feed
  • Shelf Life: 6 months (3-batch accelerated stability, 25 ± 2 °C / 60 ± 5% RH)
  • Port of Loading: Ningbo / Shanghai, China

Downloads

Technical documents available on request — issued under NDA-free standard terms for procurement records.

📄 TDS — TosMIC (EN) Request via inquiry · PDF 📋 Stability Summary & COA 3-batch accelerated stability data — request via inquiry

Request a Quote or Sample

We respond within one business day. TDS, batch COA and route consultation available on request.

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TosMIC — CAS 36635-61-7  |  Bempedoic acid / Fludioxonil C1 synthon, DG-experienced
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